New Step by Step Map For CX-5461
5c–d). CX-5461-mediated S33 phosphorylation of RPA was independent of the cell cycle stage and wasn't limited to your nucleoli in HR-deficient cells. Consequently, the development of ssDNA constructions in CX-5461 handled cells can lead to replication fork stalling and ATR activation with HRD exacerbating CX-5461-mediated replication tension an